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68Ga-DOTATOC Versus 68Ga-DOTATATE PET/CT in Functional Imaging of Neuroendocrine Tumors Thorsten D. Poeppel1, Ina Binse1, ... Because most patients received the 68Ga-DOTATOC scan as the initial imaging procedure, potential sequence effects cannot be ruled out.
68Ga-DOTATOC PET in Pediatric Oncology Presented to: Society Nuclear Medicine Medical Imaging ... •Three indications for scan Detection of unknown primaries (n=13)) Initial tumor staging (n=36) Post therapy follow up (n=35) •TP, TN, FP, and FN
68Gallium Information Session Michael Graham, PhD, MD Dominique Delbeke, MD, PhD ... Scan Results (Needs to be updated) • Ga-68 DOTATOC positive in only 1/22 patients presenting with symptoms / labs suggestive of elevated serotonin without
Scan dose 70 MBq (1.6 MBq/kg) Ga-68 DOTATOC Scan delay 30 minutes post injection Acquisition Parameters 2 min/bed, TrueV, HD•PET reconstruction CT 120 kV, 210 ref mAs 3mm slice thickness 2. Created Date:
NET, who had undergone triple-phase contrast-enhanced 68Ga-DOTATOC PET/CT between June 2006 and July 2008 at the Charit´e–University Hospital/Berlin, ... within the area of the abdominal triple-phase CT scan were considered in this study. Images were evaluated in coronal, axial,
RESEARCH Open Access Magnetic resonance imaging, computed tomography, and 68Ga-DOTATOC positron emission tomography for imaging skull base meningiomas with infracranial extension treated
Dotatoc scan. The PET scan shows an intense uptake in the above described mass. Figure 3. First case. Whole body pre-operative 68Ga-Dotatoc PET/CT scan showing an intense uptake in the right lung mass. Follow-up 68Ga-Dotatoc
68Ga-DOTATOC PET/CT scan from June 2009 showing increased uptake of radiotracer in the processus uncinatus of the pancreas (arrow), with a maximum standardized uptake value (SUV max) of 9. Physiological accumulation in the liver (L) and kidneys (K). 1.
A 68Ga-DOTATOC PET scan was performed for staging and detection of possible metastases. 68Ga-DOTATOC (tracer) is a somatostatin receptor agonist which reflects the expression of somatostatin receptors on the tumour surface. The 68Ga ...
computed tomography and PET-computed tomography images of 68Ga DOTATOC scan showing no significant radiotracer uptake in the histologically proved low grade left bronchial mucoepidermoid carcinoma (case 1). Jindal et al. Journal of Medical Case Reports 2010, 4:277
• FLT, F-DOPA, Ga-68 DOTATOC/DOTATATE 7 March 7, 2013 – Final Decision CMS Expands Local Coverage Options ... 30-day window for entering post-PET form after scan). 31 FDG-PET NOPR Logistics Claims DOS on or after June 11, 2013
RESEARCH ARTICLE Gastroenteropancreatic Neuroendocrine Tumors: Standardizing Therapy Monitoring with 68Ga-DOTATOC PET/CT Using the Example of Somatostatin Receptor
multiphase Ga-68 DOTATOC PET/CT: the potential role of arterial hyperperfusion Nils F. Schreiter1, Martin Maurer2, ... cluding an intestinal scan during arterial enhance-ment might improve the detection of primary NETs in this location even further.
Scan Results (N=127) • Ga-68 DOTATOC positive in only 3/27 patients presenting with symptoms / labs suggestive of elevated serotonin without diagnosis of NET (2 false positive, 1 unconfirmed) • Ga-68 DOTATOC identified primary tumor in 16/25 pts with
DOTATOC PET/ CT scan of a patient with metastatic neuroendocrine tumor. RADIOLOGY UPDATE DECEMBER 2011 4 (continued on next page) Sectional Update Diagnostic Medical Sonography Program by Stephanie Ellingson, BA, RDMS, RVT, RDCS, RT(R),
scan, three-dimensional PET acquisition was carried out for 5 to 8 minutes per bed position. The PET data were ... DOTATOC PET/CT for the diagnosis of primary pulmonary carcinoids remains to be established due to the lack of specific studies.
Cancer Therapy: Clinical Intraindividual Comparison of Selective Arterial versus Venous 68Ga-DOTATOC PET/CT in Patients with Gastroenteropancreatic Neuroendocrine Tumors
PET/CT Specific biomarkers: 68Ga-DOTATOC PET PET/CT Brain Heart Liver/spleen Lungs 58 year-old male. History of removal of carcinoid ... PET/CT Scan duration: 10 min 44 year-old male (6’, 118 lbs) with recent diagnosis of lung cancer. Smoker for 26 years.
A CT scan followed as did an Octreoscan and blood work. The diagnosis was high-receptor carcinoid tumors, a midgut primary tumor in the mesentery, ... Ga-68 DOTATOC PET/CT before the second cycle. Staff Sergeant Barber receiving his 2nd PRRT treatment
Hepatic arterial infusion enhances DOTATOC radiopeptide therapy in patients with neuroendocrine liver metastases Clemens Kratochwil, Ruben Lo´pez-Benı´tez1, Walter Mier, Sabine Haufe,
ue following a positive scan is the use of beta emitters labelled to ... Gallium-68 has suitable physical properties with a ... NET 68Ga-DOTATOC had a sensitivity of 97%, a specificity of 92% and an overall accuracy of 96% ...
imaging time point (68Ga-DOTATOC or Ocretotid-Scan) with an extensive systemic tumor spread underwent the systemic PRRT approach (i.v. DOTATOC-Therapy). CEUS and CE-CT were performed as part of our clinical standard procedures and within the approved
scan, an accessory spleen was present in 16% (1, 4). In 80%, the accessory spleen is located at or near the splenic hilum. ... DOTATOC-PET/CT after intravenous injection of 206 MBq 68Ga DOTATOC; the axial and coronal planes show an in-
TÍTULO / TITLE: - Diagnostic role of Gallium-68 DOTATOC and Gallium-68 DOTATATE PET in patients with neuroendocrine tumors: a meta-analysis. ... be more sensitive and specific than 68Ga-DOTATOC PET scan. -----  TÍTULO / TITLE: - Is laparoscopic approach for pancreatic ...
PET/CT -Scan, using 68 Ga -DOTATOC, reveals disseminated bone metastases, which could not be observed with any other imaging modality. Fig. 1. Comparison of 18 F-FDG, 111 In -OctreoScan and 68 Ga - DOTATOC in the same patient
The SMS analog DOTATOC (DOTA-D-Phe1-Tyr3-octreotide) was developed for imaging as well as for therapy. 5,6 DOTA-D-Phe1-Tyr3-Thr8 ... Pre-PRRNT SSTR PET/CT; B: 177Lu-DOTATOC whole-body post-therapy scan 68 hours after the first PRRNT demonstrates intense uptake in the hepatic metastases; C1 ...
Scan of In-111 MAb. 7 Days Post Intra Peritoneal Admin. Scan of In-111 MAb. Yttrium - 86 Applications: ... (DOTATOC), 4400 MBq. Indium-111 Octreotide (250 MBq) Diagnostic Scan. In-111 Octreotide (7000 MBq) for Therapy. Lutetium-177 Octreotate (7400 MBq)
DOTATOC • Somatostatin analogue • A high density of somatostatin receptors is found on many tumors, ... Correlating CT-scan. SPECT / CT mit 111In-Octreotide. Nuclear Medicine 68Ga-DOTATOC-PET • Highly specific for visualisation of somatostatin
from serial gamma camera scan data (OLINDA) Slides are not to be reproduced without permission of author. Known Toxicities of High Dose Radiation > 100 years clinical experience with XRT ... Isotope chelates Y-90-DOTATOC
A repeat scan, performed 3 days later, showed identical results. A careful comparison of all available 68Ga-DOTATOC images (Figs 1A to 1D) revealed a slightly increased ... 68Ga-DOTATOC and 111In-octreotide after the ﬁrst cycle of 90Y-DOTATOC.
B, 68Ga-DOTATOC-PET/CT scan performed in March, 2012. Prominent somatostatin-receptor expression projecting onto most of the previously known tumor manifestations. E492 Bickmann et al SDHC Mutation in Malignant Paraganglioma J Clin Endocrinol Metab, March 2014, 99(3):E489–E496.
68Ga-DOTATOC/DOTATATE PET/CT scanning which provide higher sensitivity and speci- ... whole-body acquisition is used, the scan speed should not exceed 3–5 cm/minute. Using a higher scan speed may result in failure to recognise small somatostatin
DOTATOC abdominal scan. C CT after treatment: the liver lesion is no longer visible. D Post-treatment 1In-DOTATOC transaxial scan: pathological uptake is still evident in the 8th segment of the liver. K, Kidney; S, spleen . 70 Table 2.
when analysing a receptor scan (OctreoScan or receptor PET/CT). On the other hand, false negatives may occur ... 90Y-DOTATOC or at least 20 GBq of 177Lu-DOTATATE 12. In 10 years of clinical trials, phase I and II studies demonstrated that PRRT is able
DOTATOC/TATE are the most suitable radiopeptides for treating NETs.177Lu-DOTATATE has been reported to be ... scan time of no more than 24 minutes and a total PET/CT acquisition of about 30 minutes. The reconstructed PET/CT images were displayed in
scan was done acquiring static emission data for 4 min-utes per FOV. PET images were reconstructed by using an iterative algo- ... DOTATOC-PET for treatment planning of intracranial complexly shaped meningiomas. Up to now the follow up
scan 4 months post dotatoc therapy showed pro-gressive disease. He underwent a further 5 GBq of dotatoc-90Yttrium therapy with significant uptake in the neck lesion but no uptake in the lung and brain metastases. He died 6 months after his second do-
parathyroid gland and octreotide scan was positive. In conclusion, when a focal uptake was observed in the ... DOTATOC uptake in the thyroid gland and association with thyroid pathologies. Thyroid 2009;19:381-389. 4.
position, scan and tattoo the patient to ensure both radio-therapy and nuclear medicine objectives are met with equal importance. ... tracer used, although other tracers such as 68Ga-DOTATOC are also being used where clinically indicated.
enhanced CT scan. • Palliative ... Abstract #455: Synthesis of 213Bi-DOTATOC for peptide receptor alpha-therapy of GEP-NET patients refractory to beta therapy. Remarkable responses to Bi-213-DOTATOC observed in tumors resistant to previous
of Ga -68 DOTATOC PET over In 111 octreotide scan, especially in detecting small tumors or tumors bear-ing only a low density of SSTRs.12 In a larger sub-group of patients (n = 90) with pathologically con- firmed NETs, a ...
various drugs; gallium-68 labeled to dotatoc/dotanoc for neuroendocrine tumor imaging; fluorine-18 labeled to thymidine for studying the dna function ... PEt scan is about 96% with sensitivity of >91% in detection of lymphoma lesion as compared to 56% of ct scan.
a PET/CT scan was performed with 68Ga-DOTATOC which is highly sensitive to SSR2-receptors. We found an increased uptake in paravertebral lymph node and in a small area located in the duodenum. We have successfully nailed down the primary tumor — but
Flexible scan planes . Advantages of PET/MR ... Ga-DOTATOC ; 11; C-Choline ; PET/MR and Dose Reduction ; 2D PET Acquisition (20 mCi 18F-FDG) + non-optimized CT to 3D PET (10 mCI 18F-FDG) to optimized CT (TCM, bismuth shields, etc.)
Both 90Y-DOTATOC and 177Lu-DOTATATE have been demonstrated to improve symptoms and reduce tumor size in metastatic NETs17. The success of these therapies depends on the demonstration of tumoral uptake on pre-treatment scan - ning, ...
PET scan was performed from the lower thighs, with 6 bed positions (3 min per bed). ... (68Ga-DOTATOC, 68Ga-DOTANOC). Ga-DOTANOC was originally developed to study NE carcinomas and in this set-ting it has shown to have better figures of merits for the study
resonance imaging and gallium68-DOTATOC positron emission tomography scan demonstrated the presence of a 1.2 x 2 cm lesion in the pancreatic head and a liver metastatis. Pancreatic endoscopic ultrasound with fine
scan is performed for the following reasons: recently performed state-of-the-art whole-body CT, therapy mon- ... DOTATOC (100 MBq) were administered, respectively. All patients with predominant abdominal studies were asked to drink 1500 ml of mannitol 2% as a negative
Scan and High Thyroglobulin Level. Bertagna F; Giubbini R et al. Clinical Nuclear Medicine 2009 34(11) ... [68Ga]DOTATOC in recurrent differentiated thyroid cancer: preliminary data Middendorp M et al. Q J Nucl Med Mol Imaging. 2010 Feb;54(1):76-83 .
DOTATOC PET Acquisition 58 PET Myocardial Perfusion Combined with CT Angiography in Detection of Post- Revascularization Ischemia Customer Care 60 Tips & Tricks: Setting Scan Range on the Biograph mCT Flow ... sive rescanning, we extend the scan time